Leuprorelin Acetate

CAS: 74381-53-6
Molecular Formula: C59H84N16O12
Molecular Weight: 1209.41
Product description:A common hormonal malignant tumor drug resistance, for the gonadotropic hormone releasing hormone (LHRH a decapeptide) nine peptide synthesis of analogues of light c gonadorelin acetate, LH and RH antagonists, LHRH is produced by the hypothalamus, suction release before it can cause pituitary gonadal hormone and follicle-stimulating hormone (FSH) and luteinizing hormone (LH) is generated. This product because of the structure similar to the LHRH, acting on the anterior pituitary after also has the function of prompt release of FSH, LH, thus improve the serum concentrations of testosterone and dihydro testosterone. Clinical maintenance therapy for advanced prostate cancer, but in the application of this product about a week later, have a number of receptor activity decreases, the secretion of gonadotropin can also be reduced. In 2 ~ 4 weeks later, testosterone and dihydro testosterone levels can drop to castration level. After the drug withdrawal, gonadotropin and testosterone can be recovered to normal levels.