Homotaurine

Source high-purity Homotaurine (3-Aminopropanesulfonic Acid), a versatile GABA-mimetic compound widely utilized in cosmetic and pharmaceutical research. Known for its soothing, anti-irritant, and skin-conditioning properties, it is an ideal active ingredient for sensitive skin care formulations and neuroprotective studies. Secure premium quality Homotaurine for your next innovative product development. High-quality raw material. Get a quote today!

Product Specification

• Product Name: Homotaurine (3-Aminopropanesulfonic Acid)
• Appearance: White crystalline powder
• CAS No.: 3687-18-1
• Molecular Formula: C₃H₉NO₃S
• Specification: Purity ≥99.0% (HPLC); Molecular Weight: 139.17 g/mol; Loss on Drying: <0.5%; Heavy Metals: <10 ppm
• Ingredient Information: Synthetic sulfonic acid derivative; Highly water-soluble; Structurally similar to taurine but with an additional methylene group; Non-toxic and non-irritating

Product Description

Homotaurine, also known as tramiprosate, is a small molecule that mimics the structure and function of gamma-aminobutyric acid (GABA). It is highly valued in the cosmetic industry for its exceptional ability to soothe irritated skin, reduce redness, and strengthen the skin barrier by promoting filaggrin synthesis. Unlike many active ingredients, Homotaurine is extremely stable and compatible with a wide range of formulation types. In pharmaceutical research, it has been studied for its potential neuroprotective effects, particularly in the context of amyloid-beta aggregation inhibition. Its dual utility in dermocosmetics for sensitivity management and in biomedical research makes it a sought-after raw material for developers focusing on gentle yet effective solutions.

Product Uses

Homotaurine is extensively used in the formulation of skincare products designed for sensitive, reactive, or compromised skin. It is a key ingredient in soothing serums, toners, and moisturizers aimed at reducing inflammation and calming irritation caused by environmental stressors or harsh treatments. Additionally, it is incorporated into post-procedure care products to accelerate skin recovery and maintain hydration. Beyond cosmetics, Homotaurine serves as a critical reagent in pharmaceutical and neuroscience research, particularly in studies investigating GABAergic pathways, neurodegenerative diseases, and protein misfolding mechanisms. It is also explored in oral care products for its potential to reduce gum inflammation.

Formulation Recommendation

Recommended Usage Level: In cosmetic formulations, typical usage levels range from 0.1% to 2.0% w/w, depending on the desired soothing effect and product type.
Addition Method: Highly water-soluble; dissolve directly in the aqueous phase of the formulation. It can be added at any stage of the process, but incorporation during the water phase heating or cooling stage is common. Ensure complete dissolution before mixing with other phases.
Compatibility: Excellent compatibility with most cosmetic ingredients, including surfactants, emulsifiers, preservatives, and other active agents like niacinamide or hyaluronic acid. Stable across a broad pH range (3.0–9.0). Does not interact negatively with metal ions. Synergizes well with other barrier-repair ingredients such as ceramides and panthenol.