Polyoxin B

Source high-purity Polyoxin B, a potent nucleoside antibiotic fungicide derived from Streptomyces cacaoi. This targeted agricultural active ingredient effectively inhibits chitin synthase, offering superior control over fungal pathogens in crops. Ideal for formulating eco-friendly biopesticides and integrated pest management solutions. High-quality raw material. Get a quote today!

Product Specification

• Product Name: Polyoxin B (Technical Grade)
• Appearance: White to off-white hygroscopic powder
• CAS No.: 19408-03-8
• Molecular Formula: C₁₃H₂₁N₅O₁₀
• Specification: Purity ≥90% (HPLC); Potency: ≥900 IU/mg; Moisture Content: <5%; pH (1% solution): 4.0–6.0
• Ingredient Information: Natural nucleoside peptide antibiotic produced by fermentation of Streptomyces cacaoi var. asoensis; Water-soluble

Product Description

Polyoxin B is a highly specific antifungal agent belonging to the polyoxin complex, renowned for its unique mode of action that inhibits chitin synthase in fungal cell walls. This mechanism prevents the polymerization of N-acetylglucosamine, leading to the accumulation of chitin oligomers and subsequent rupture of the fungal cell wall. Unlike broad-spectrum chemical fungicides, Polyoxin B exhibits exceptional selectivity, posing minimal risk to non-target organisms, beneficial insects, and mammals. Its biodegradable nature and low residue profile make it a preferred choice for sustainable agriculture and organic farming practices. As global regulations tighten on synthetic pesticides, Polyoxin B stands out as a critical tool for managing resistant fungal strains, particularly in high-value crops like fruits, vegetables, and ornamentals.

Product Uses

This ingredient is primarily utilized in the formulation of agricultural fungicides for the control of various plant diseases caused by Ascomycetes, Deuteromycetes, and Basidiomycetes. It is extensively used in crop protection products targeting rice blast, apple spot blotch, pear black spot, and gray mold in strawberries and grapes. Due to its systemic properties and rapid absorption, it is effective in both preventive and curative applications. Additionally, Polyoxin B is employed in integrated pest management (IPM) programs where resistance management is crucial, often rotated with other fungicide classes to maintain efficacy. It is also researched for potential applications in post-harvest treatment to extend the shelf life of fresh produce by suppressing fungal decay.

Formulation Recommendation

Recommended Usage Level: Typical final product concentrations range from 1% to 10% w/w for wettable powders (WP) or soluble liquids (SL), depending on target crop and disease pressure.
Addition Method: Dissolve Polyoxin B in water or aqueous buffer systems due to its high water solubility. For solid formulations, blend uniformly with carriers like kaolin or talc. Ensure pH stability between 4.0 and 7.0 during processing to maintain potency.
Compatibility: Compatible with most neutral to slightly acidic pesticides and fertilizers. Avoid mixing with strong alkaline agents (pH >8) which may degrade the nucleoside structure. Synergizes well with protective fungicides like mancozeb for broader spectrum control. Store in a cool, dry place away from direct sunlight to prevent hydrolysis.