N-Acetyl Selank Amidate

Source high-purity N-Acetyl Selank Amidate, a stabilized nootropic peptide designed for advanced neuroscience research. This modified analog of Selank offers enhanced metabolic stability and blood-brain barrier permeability, making it ideal for studying anxiolytic mechanisms and cognitive enhancement. Perfect for laboratories focused on neuropharmacology and peptide therapeutics. High-quality raw material. Get a quote today!

Product Specification

• Product Name: N-Acetyl Selank Amidate (Research Grade)
• Appearance: White to off-white lyophilized powder
• CAS No.: Not publicly assigned (Proprietary synthetic peptide analog)
• Molecular Formula: C₅₃H₇₉N₁₅O₁₄ (Approximate, based on Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH₂)
• Specification: Purity ≥98% (HPLC); Molecular Weight: ~1164.3 g/mol; Endotoxin <1.0 EU/mg
• Ingredient Information: Synthetic heptapeptide; N-acetylated at the N-terminus and amidated at the C-terminus for stability

Product Description

N-Acetyl Selank Amidate is a chemically modified version of the regulatory peptide Selank, engineered to resist enzymatic degradation and prolong biological half-life. By adding acetyl and amide groups, this analog achieves superior stability in biological fluids compared to the native peptide. It is renowned for its potential modulatory effects on the GABAergic system and brain-derived neurotrophic factor (BDNF) expression. In the realm of nootropic research, it stands out for its ability to reduce anxiety-like behaviors without sedative effects, while potentially enhancing memory consolidation and learning processes. This makes it a valuable tool for investigating novel treatments for stress-related disorders and cognitive decline.

Product Uses

This ingredient is exclusively intended for laboratory research and preclinical studies. It is widely used in neuroscience research to explore mechanisms of anxiety regulation and stress response modulation. Researchers utilize it in behavioral assays to assess cognitive performance, memory retention, and learning capabilities in animal models. Additionally, it serves as a key compound in neuropharmacological studies investigating the interaction between synthetic peptides and neurotransmitter systems, particularly GABA and serotonin pathways. It is not approved for human consumption or clinical use.

Formulation Recommendation

Reconstitution: Dissolve in sterile deionized water or PBS to create a stock solution (e.g., 1–5 mg/mL). Gentle vortexing is recommended. Aliquot and store at -20°C or -80°C.
Usage Concentration: Typical working concentrations in vivo range from 0.1–1.0 mg/kg, depending on the model. In vitro, use 1–10 μM for cell culture studies.
Compatibility: Compatible with standard physiological buffers. Avoid repeated freeze-thaw cycles. For enhanced stability in solution, add 0.1% BSA. Synergizes well with other nootropic agents like Racetams in combination studies, though careful dosing is required to avoid confounding variables.