Acetyl Hexapeptide-38

Source premium Acetyl Hexapeptide-38, a specialized biomimetic peptide designed to enhance skin firmness and elasticity by targeting integrin signaling. This high-performance active ingredient supports the dermal-epidermal junction, offering visible lifting effects for anti-aging formulations. Ideal for serums, creams, and eye care products. Competitive bulk pricing for global cosmetic manufacturers. High-quality raw material. Get a quote today!

Product Specification

• Product Name: Acetyl Hexapeptide-38
• Appearance: White to off-white lyophilized powder or clear liquid (if supplied as a solution)
• CAS No.: 1406366-98-7
• Molecular Formula: C₃₄H₆₅N₁₃O₉
• Specification:
  • Purity: ≥ 98% (HPLC)
  • Molecular Weight: 783.9 g/mol
  • Sequence: Acetyl-Lys-Leu-Gly-Glu-Leu-Lys-NH₂ (or similar variant depending on specific supplier synthesis, commonly associated with Integrin stimulation)
  • Solubility: Soluble in water and glycols
  • Storage: Store at 2-8°C for long-term stability; protect from light
• Ingredient Information: INCI Name: Acetyl Hexapeptide-38. A synthetic peptide that mimics the activity of endogenous peptides involved in cell adhesion and communication between the epidermis and dermis. It is often marketed for its ability to reinforce the skin's structural integrity and improve firmness.

Product Uses

Product Description:
Acetyl Hexapeptide-38 is a cutting-edge bioactive peptide that targets the skin's structural foundation by stimulating integrin expression. Integrins are crucial proteins that anchor the epidermis to the dermis, ensuring skin cohesion and resilience. By enhancing this connection, Acetyl Hexapeptide-38 helps combat sagging and loss of elasticity, delivering a visible lifting effect. It is highly valued in the anti-aging market for its ability to improve skin density and firmness without invasive procedures. Its water-soluble nature and stability make it a versatile addition to modern skincare formulations aimed at mature or aging skin.

Applications:
Acetyl Hexapeptide-38 is suitable for a wide range of personal care products, including:

• Firming Serums & Ampoules: High-potency treatments for lifting and contouring.
• Anti-Aging Creams & Lotions: Day and night moisturizers targeting loss of elasticity.
• Eye Care Products: Eye creams and gels to address drooping eyelids and crow's feet.
• Neck & Décolleté Care: Specialized formulations for areas prone to sagging.
• Post-Procedure Skincare: Supportive care after aesthetic treatments to maintain results.

Formulation Suggestions:
Recommended Usage: Typically used at concentrations between 0.01% and 0.1% of the pure peptide powder in the final formulation. If using a pre-diluted solution (e.g., 100 ppm or 1000 ppm), adjust usage rate according to supplier guidelines (often 1-5% of the solution).

Method of Addition:

• Phase: Add during the cool-down phase (below 40°C / 104°F) to preserve peptide integrity. Avoid high heat which can denature the peptide structure.
• Solubility: Fully soluble in water. Pre-dissolve in distilled water, glycerin, or propanediol before adding to the main batch to ensure uniform distribution.

Compatibility & Synergy:

• pH Stability: Optimal stability in pH range 5.0–7.0. Avoid highly acidic or alkaline environments.
• Synergistic Ingredients: Works well with other firming agents like Matrixyl (Palmitoyl Pentapeptide-4), Hyaluronic Acid for hydration, and Niacinamide for barrier support. Can be combined with antioxidants (Vitamin C/E) for comprehensive anti-aging benefits.
• Preservation: Ensure adequate preservation as peptide solutions are susceptible to microbial growth. Compatible with most common cosmetic preservatives.
• Chelating Agents: Use EDTA or similar chelators to sequester metal ions that may catalyze peptide degradation.