Moclobemide is advised to be beneath baneful in balance compared to earlier antidepressants, such as the tricyclic antidepressants and nonselective, irreversible MAO inhibitors,making it a safer antidepressant in the aged or humans with concrete disorders. Of 18 humans who overdosed on moclobemide during analytic trials, all recovered absolutely and moclobemide was advised to be safe for in as able-bodied as outpatient use.
Intoxications with moclobemide as individual abettor are usually mild; however, if accumulated with tricyclic or SSRI antidepressants the balance abundant added baneful and potentially fatal. Moclobemide, is adopted by doctors for patients who are at accident of suicide, due to moclobemide's low toxicity in overdose. Patients with alloyed intoxications may appearance astringent or life-threatening affection and should be hospitalized. Treatment is abundantly appropriate and should be aimed at aliment of the basic functions.