Terlipressin Acetate

Terlipressin Acetate

Cas No.: 14636-12-5
Sequence: Gly-Gly-Gly-c[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,(Disulfide bridge: Cys-Cys)
Molecular Formula: C52H74N16O15S2 
Molecular Weight: 1227.37
Appearance:  White powder
Purity (HPLC): >98.0%
Single Impurity (HPLC): <1.0%
Amino Acid Composition: 10% of theoretical
Peptide Content (N%): >80.0%
Water Content (Karl Fischer): <10.0%
Specific Rotation (20/D): -95.0~-105.0o (C=1 1%HAc)
Acetate Content (HPIC): <15.0%
Description About Terlipressin Acetate Cas 14636-12-5
The sequence of Terlipressin Acetate is adding three Glys based on lysine vasopressin. Therefore, in clinical manifestations, Terlipressin Acetate undergoes enzymatic degradation in the body to produce active metabolites. The main active metabolite is lysine vasopressin, so terlipressin has a slower onset of action, but its effect lasts longer. In terms of the metabolite of Terlipressin Acetate: lysine vasopressin will be further degraded in the liver, kidney and other tissues.

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