CAS NO.: 148553-50-8
Molecular Formula: C8H17NO2
Molecular weight: 159.229
Appearance: White to off-white crystalline powder
Assay Content by HPLC: Min. 98%-101%
Specific Rotation: + 10° ~+12°
Chloride: ≤ 0.1 %
Mesh size: 100% pass 80mesh
Solubility: Soluble in Ethanol
Loss on drying %: ≤ 1.0 %
Heavy metals: ≤20 PPM
Be used in food pharmaceutical and cosmeceutical
1. Pharmacological efficacy: Pregabalin is a novel γ-aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release.
2. The main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.
3. Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration.Pregabalin can also be used to treat pain and anxiety.
Pregabalin is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. Although the exact mechanism of action is unknown, pregabalin selectively binds to alpha2delta (A2D) subunits of presynaptic voltage-dependent calcium channels (VDCCs) located in the central nervous system (CNS). Binding of pregabalin to VDCC A2D subunits prevents calcium influx and the subsequent calcium-dependent release of various neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P, from the presynaptic nerve terminals of hyperexcited neurons; synaptic transmission is inhibited and neuronal excitability is diminished. Pregabalin does not bind directly to GABA-A or GABA-B receptors and does not alter GABA uptake or degradation.
Shelf Life: Two years if sealed and stored away from direct sun light.
Packing & Storage: Store in cool & dry place. Keep away from strong light and heat.
Please at any time if you are interested in Pregabalin.
If you want to know about Pregabalin price , please call our Customer Services Hotline +86 592 5365887 or send the email to email@example.com.
We sincerely welcome friends from all over the world to contact us. After sending an online inquiry, we will reply to you as soon as possible. If you do not get any response on time please call us.
We are committed to meeting customers' unique needs by providing comprehensive and professional service, enjoying a good reputation among our business partners and customers for high-quality products, excellent after-sales services, competitive prices, and prompt shipping.
Shanghai Office: 168 Zhonggu Rd, Pingpu District, Shanghai, China.
Xiamen Office: 106, Houdaixi Road, Xiamen, China.
Tel: +86 592 5365887
Mobile phone: +86 189 6515 7632
E-mail:firstname.lastname@example.org(Reply within 1 working day)
WhatsApp/QQ/Skype/Mob: +86 13696950872
Our VP sales manager has over 25 years of management experience in all leadership roles.
WhatsApp/QQ/Skype/Mob: +86 17306002753
Estella Zeng is responsible for all lead generation, customer service, and marketing operations.
WhatsApp/QQ/Skype/Mob: +86 18965157632
Jerry Bai is responsible for the global sales, service and channel expansion into the European market.
Supplying safe and efficient ingredients and formulas for cosmetic and nutritional products.
Offering the best product design to customers with natural and high-quality raw materials.
Honesty Profession Win-win Cooperation