Synonym: Dadibutol, Myambutol; Ethambutol dihydrochloride
Chemical Name: 1-Butanol,2,2'-(ethylenediimino)di-,dihydrochloride,(+)-
CAS NO.: 1070-11-7
Molecular Formula: C10H26Cl2N2O2
Molecular Weight: 277.23
Appearance: White Powder
Melting Point: 201°C (393.8°F)
Solubility:Easily soluble in cold water, hot water. Soluble in alcohol.
Use: Antibacterial (tuberculostatic)
Main Function: Pharmaceutical Intermediates
Ethambutol hydrochloride is an antitubercular agent that inhibits the transfer of mycolic acids into the cell wall of the tubercle bacillus. It may also inhibit the synthesis of spermidine in mycobacteria. The action is usually bactericidal, and the drug can penetrate human cell membranes to exert its lethal effect. Ethambutol Hydrochloride is the hydrochloride salt form of ethambutol, an ethylenediamine derivative with antibacterial activity, specifically effective against mycobacteria. Although the exact mechanism of action of ethambutol hydrochloride is unknown, ethambutol hydrochloride inhibits the transfer of mycolic acids into the cell wall of bacteria, which impedes bacterial cell growth. This agent may also interfere with RNA synthesis or inhibit other cell metabolism, thereby preventing cell multiplication and causing cell death.
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