Cefbuperazone

Cefbuperazone

CAS NO.: 76610-84-9 
Molecular Formula: C22H29N9O9S2
Molecular weight: 627.648
Appearance: White Powder
Water content: Not more than1.0%
pH: Between4.0~6.0
Heavy metals:  Not more than 10ppm
Arsenic:  Not more than 2ppm
Absorbance(265nm):  Between255~285
Sulphated ash: Not more than 0.2%
Specific optical Rotation:  Between +48°~ +56°
Purity:  NLT99.0%
Application: 
Used to cure Septicemia, chronic bronchitis, pneumonia, pulmonary purulent disease, endocarditis, cholecystitis caused by sensitive bacteria such as Escherichia coli, Serratia, common and exotic proteobacteria, Haemophilus influenzae, pneumococcal bacteria , peritonitis, cystitis, etc. 
Description:
Cefbuperazone is a semisynthetic second-generation cephalosporin with antibacterial activity. Cefbuperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Storage:  Store in a tightly closed container at low temperature.

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