Sodium Starch Glycolate
CAS : 9063-38-1
Product Description :
Sodium starch glycolate, or SSG, is a common ingredient in many pharmaceutical pills, although it is not a medicine. SSG is the sodium salt of a carboxymethyl ether of starch. It is commonly used as a rapid disintegrant, a chemical that promotes the rapid distingetration and immediate release of orally administered drugs. It coats the pills keeping the medicine in, but releases the medicine rapidly upon contact with water.
Sodium starch glycolate works by rapidly absorbing water. When medicines are contained within tablets or granules, they are coated with sodium starch glycolate. As soon as the glycolate comes in contact with water, it rapidly absorbs it. This results in a large amount of swelling, which leads to the rapid disintegration of the tablets or granules and subsequent release of the medication.
While the vast majority of sodium starch glycolate is used as a disintegrant in pills, it has also been used in the food industry. SSG has been used as a suspending vehicle, a food stabilizer and as an anti-aging agent for bread. It is has also been used in the manufacture of ice cream. In Japan, the chemical industry has used SSG in the manufacture of cream, shampoo and other Japanese products. SSG is also been known to raise plasma pressure and increase blood volume. Injection preparations of SSG are available for use in hemorrhagic shock and trauma.
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