Nattokinase

Nattokinase

CAS : 133876-92-3
Product Description :
Nattokinase is an enzyme extracted and purified from a Japanese food called Natto. Natto is a food made from fermented soybeans that has been eaten in Japan for many years. Natto is produced by fermentation by adding the bacterium Bacillus natto, a beneficial bacteria, to boiled soybeans. The resulting nattokinase enzyme is produced when the bacterium acts on the soybeans. While other soy foods contain enzymes, it is only the natto preparation that contains the specific nattokinase enzyme.
Nattokinase is a clot-buster and blood thinner. Nattokinase (nk) produces a prolonged action (unlike antithrombin drugs that wear off shortly after IV treatment is discontinued) in two ways: it prevents coagulation of blood and it dissolves existing thrombus.
The mechanism for this enzyme to potentiate fibrinolysis is not fully understood. Subtilisin Nattokinase (NAT) is reported not to possess plasminogen activator activity but appears to directly digest fibrin by limited proteolysis. However, this direct cleavage of fibrin does not seem to account for all of the enhancement of the fibrinolytic activity that has been observed without affecting the fibrinolytic cascade.

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