Barbituric acid derivatives

Barbituric acid derivatives

CAS : 67-52-7
Molecular Formula : C4H4N2O3
Molecular Weight : 128.09
Product Description :
Barbituric acid or malonylurea or 6-hydroxyuracil is an organic compound based on a pyrimidine heterocyclic skeleton. It is an odorless powder soluble in hot water. Barbituric acid is the parent compound of barbiturate drugs, although barbituric acid itself is not pharmacologically active. The compound was discovered by the German chemist Adolf von Baeyer on December 4, 1864, the feast of Saint Barbara (who gave the compound its namesake), by combining urea and malonic acid in a condensation reaction.Malonic acid has since been replaced by diethyl malonate, s using the ester avoids the problem of having to deal with the acidity of the carboxylic acid and its unreactive carboxylate.

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