CAS No.: 9007-43-6
Molecular Weight: 884.88728
Molecular Formula: C42H52FeN8O6S2
Appearance: Red powder
Description About Cytochrome C CAS 9007-43-6
Cytochrome c is involved in the mitochondrial electron-transfer chain and accepts an electron from cytochrome c1 and transfers it to cytochrome c oxidase. This electron is subsequently used in the reduction of oxygen, where four electrons are needed. This means that actually four cytochrome c transfer an electron to cytochrome c oxidase, where one molecule of O2 is converted to two molecules of water.
Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c.
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