Annonacin

Annonacin

CAS: 111035-65-5
Purity:99%
Storage:Avoid exposure to sunlight,Keep dry
Product description :Along with other acetogenins, annonacin blocks mitochondrial complex I (NADH-dehydrogenase), which is responsible for the conversion of NADH to NAD+ and the build-up of a proton gradient over the mitochondrial inner membrane. This effectively disables a cell's ability to generate ATP via an oxidative pathway, ultimately forcing a cell into apoptosis or necrosis.
 

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