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Where to buy Isopropyl myristate?

CAS No.: 110-27-0

Molecular Formula: C17H34O2

Molecular Weight: 270.45

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What is Spilanthol?

CAS: 25394-57-4

Molecular Formula: C14H23NO
Molecular weight:221.33900
Density:0.896g/cm3
Boiling point:384.7°C
Flash point:234°C
Shelf life:2 years
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What is Annonacin?

CAS: 111035-65-5

Purity:99%
Storage:Avoid exposure to sunlight,Keep dry
Description
Annonacin is extracted from the annonaceous plant. i.e. pawpaw fruit contains a high concentration of Annonacin, which is toxic to cortical neurons. Annonacin induced growth arrest and apoptosis in ERα-related pathways in MCF-7 cells. Moreover, Annonacin attenuated MCF-7 xenograft tumor growth while inhibiting ERα, cyclin D1 and Bcl-2 protein expressions in nude mice. Annonacin-induced ATP depletion causes the retrograde transport of mitochondria to the cell soma and induces changes in the intracellular distribution of tau in a way that shares characteristics with some neurodegenerative diseases. Annonacin caused significant cell death in various cancer cell lines. T24 bladder cancer cells at the S phase were more vulnerable to the cytotoxicity of Annonacin. Furthermore, Annonacin activated p21 in a p53-independent manner and arrested T24 cells at the G1 phase. It also induced Bax expression, enhanced caspase-3 activity, and caused apoptotic cell death in T24 cells.
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