Methotrexate Disodium for Injection
Synonyms: Methotrexate disodium salt; 7413-34-5; Sodium methotrexate; METHOTREXATE SODIUM; MTX disodium
CAS NO.: 7413-34-5
Molecular Formula: C20H20N8Na2O5
Molecular Weight: 498.411
Appearance: Light yellow or dark yellow powder
Use: Animal Pharmaceuticals
Main Function: pharmaceutical intermediate
Application: pharma grade or research purpose
Methotrexate Sodium is the sodium salt of methotrexate, an antimetabolite with antineoplastic and immunomodulating properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant properties.
Ecological data: This substance may be harmful to the environment and specific attention should be paid to water bodies.
Nature and stability: It will not decompose if used and stored in accordance with specifications.
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